Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | KDM6B | O15054 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29364884 | 1.00 | FEN1 (0.46) | FEN1L3MBTL1POLBTHRBEGFR | |
| SCHEMBL30643799 | 0.88 | FEN1 (0.46) | FEN1L3MBTL1POLBEGFRSRC | |
| SCHEMBL30436019 | 0.81 | ELANE (0.48) | POLBALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL25217083 | 0.81 | ELANE (0.48) | POLBALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29956951 | 0.77 | FEN1 (0.45) | FEN1L3MBTL1EGFRSRCERN1 | |
| SCHEMBL3223827 | 0.77 | ALDH1A1 (0.61) | FEN1POLBEGFRSRCERN1 | |
| SCHEMBL29954607 | 0.75 | POLB (0.61) | L3MBTL1POLBTHRBEGFRALDH1A1 | |
| SCHEMBL16381206 | 0.71 | FEN1 (0.49) | FEN1L3MBTL1EGFRSRCALDH1A1 | |
| SCHEMBL6487828 | 0.71 | KDM4E (0.44) | L3MBTL1POLBERN1ALDH1A1KMT2A | |
| SCHEMBL11078500 | 0.71 | FEN1 (0.52) | FEN1L3MBTL1EGFRSRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116249531-A | Compositions and methods for activating pyruvate kinase | 密执安大学评议会 | 2023-06-09 | — | — | CN | disclosed |
| EP-4185293-A1 | COMPOSITIONS AND METHODS FOR ACTIVATING PYRUVATE KINASE | The Regents of The University of Michigan (US) | 2023-05-31 | — | — | EP | disclosed |