Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 6/20 | 0.43 |
| ▸ | UMPS | P11172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5079246 | 0.95 | KDM4E (0.46) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL4361970 | 0.95 | KDM4E (0.46) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL3051902 | 0.78 | KDM4E (0.45) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL9234118 | 0.78 | KDM4E (0.45) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8463341 | 0.78 | KDM4E (0.46) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8466249 | 0.78 | KDM4E (0.46) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL30697964 | 0.76 | KDM4E (0.46) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8465320 | 0.76 | SMN1; SMN2 (0.46) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL11281347 | 0.76 | KDM4E (0.46) | KDM4EGMNNLMNAMAPTBLM | |
| SCHEMBL8465125 | 0.76 | SMN1; SMN2 (0.46) | KDM4EGMNNLMNAMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034802-B2 | Administration of TLR7 ligands and prodrugs thereof for treatment of infection by hepatitis C virus | ANADYS PHARMACEUTICALS, INC. (US) | 2011-10-11 | — | — | US | disclosed |