Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 13/20 | 0.63 |
| ▸ | HTR2C | P28335 | 5/20 | 0.63 |
| ▸ | HTR2B | P41595 | 5/20 | 0.63 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25293535 | 0.84 | HTR2A (0.62) | HTR2AHTR2CHTR2B | |
| SCHEMBL25245902 | 0.84 | HTR2A (0.62) | HTR2AHTR2CHTR2B | |
| SCHEMBL25285776 | 0.84 | HTR2A (0.58) | HTR2AHTR2CHTR2B | |
| SCHEMBL25288251 | 0.84 | HTR2A (0.67) | HTR2AHTR2CHTR2B | |
| SCHEMBL25774281 | 0.82 | HTR2A (0.55) | HTR2AHTR2CHTR2B | |
| SCHEMBL31358085 | 0.81 | HTR2A (0.58) | HTR2AHTR2CHTR2B | |
| SCHEMBL25293945 | 0.81 | HTR2A (0.58) | HTR2AHTR2CHTR2B | |
| SCHEMBL25293441 | 0.80 | HTR2A (0.70) | HTR2AHTR2CHTR2B | |
| SCHEMBL31358003 | 0.80 | HTR2A (0.50) | HTR2AHTR2CHTR2B | |
| SCHEMBL25244788 | 0.78 | HTR2A (1.00) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4447954-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | Icahn School of Medicine at Mount Sinai (US) | 2024-10-23 | — | — | EP | disclosed |
| WO-2023114472-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023114472-A1 | HETEROCYCLIC COMPOUNDS AS 5HT2A BIASED AGONISTS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-06-22 | — | — | WO | disclosed |