Carboxynaphthol

Carboxynaphthol

SCHEMBL25244

O=C(O)c1ccc2ccccc2c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB2

The experimentally established mechanism targets of Carboxynaphthol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 1.00
WDR5 P61964 1/20 0.68
NR4A1 P22736 1/20 0.61
NR4A2 P43354 1/20 0.61
NR4A3 Q92570 1/20 0.61
CYP1B1 Q16678 3/20 0.60
CYP1A1 P04798 2/20 0.60
ABCG2 Q9UNQ0 1/20 0.60
CFTR P13569 1/20 0.58
HSD17B10 Q99714 3/20 0.55
TSHR P16473 2/20 0.55
HPGD P15428 2/20 0.55
THRB P10828 1/20 0.55
CYP2C9 P11712 1/20 0.55
ALOX12 P18054 1/20 0.55
ATIC P31939 1/20 0.55
KDM4E B2RXH2 3/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
MAPT P10636 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carboxynaphthol SCHEMBL3770341 1.00 LDHA (1.00) LDHAWDR5NR4A1NR4A2NR4A3
Carboxynaphthol SCHEMBL2099330 1.00 LDHA (1.00) LDHAWDR5NR4A1NR4A2NR4A3
Carboxynaphthol SCHEMBL7257660 0.98 LDHA (0.96) LDHAWDR5NR4A1NR4A2NR4A3
Carboxynaphthol SCHEMBL28259598 0.98 LDHA (0.96) LDHAWDR5NR4A1NR4A2NR4A3
Carboxynaphthol SCHEMBL27673953 0.98 LDHA (0.96) LDHAWDR5NR4A1NR4A2NR4A3
Carboxynaphthol SCHEMBL25371193 0.98 LDHA (0.96) LDHAWDR5NR4A1NR4A2NR4A3
Carboxynaphthol SCHEMBL25369919 0.98 LDHA (0.96) LDHAWDR5NR4A1NR4A2NR4A3
Carboxynaphthol SCHEMBL1458046 0.98 LDHA (0.96) LDHAWDR5NR4A1NR4A2NR4A3
Carboxynaphthol SCHEMBL10943009 0.98 LDHA (0.96) LDHAWDR5NR4A1NR4A2NR4A3
Carboxynaphthol SCHEMBL5964608 0.98 LDHA (0.96) LDHAWDR5NR4A1NR4A2NR4A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 24345 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4745137-A1 GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-05-20 EP claimed
EP-4745135-A1 COMPOUND BASED ON THIO-GLUTARIMIDO ISOINDOLINONE SKELETON AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-05-20 EP claimed
CN-122070278-A Bifunctional protein degradation agent containing aryl substituted heteroaryl and application thereof 标新生物医药科技(上海)有限公司 2026-05-19 CN claimed
CN-122036704-A Free base crystal form or acid salt of biaryl compound, preparation method and medical application thereof 江苏豪森药业集团有限公司 2026-05-15 CN claimed
US-12624050-B2 Three fused ring derivative-containing salt or crystal form and pharmaceutical composition thereof SHANGHAI HANSOH BIOMEDICAL CO., LTD. (CN) 2026-05-12 US claimed
US-20260125390-A1 SOLID FORMS OF MACROCYCLIC COMPOUNDS, SALTS AND FORMULATIONS THEREOF, AND METHODS OF PREPARING AND USING THE SAME KURA ONCOLOGY INC (US) 2026-05-07 US claimed
EP-4720073-A1 SOLID FORMS OF A MACROCYCLIC FARNESYLTRANSFERASE INHIBITOR AND FORMULATIONS THEREOF, AND METHODS OF PREPARING AND USING THE MACROCYCLIC COMPOUND AND ITS SOLID FORMS Kura Oncology, Inc. (US) 2026-04-08 EP claimed
EP-4721739-A1 CSF-1R INHIBITOR PHARMACEUTICAL COMPOSITION, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF Abbisko Therapeutics Co., Ltd. (CN) 2026-04-08 EP claimed
EP-4722207-A1 OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) 2026-04-08 EP claimed
US-4352860-A Thermosensitive recording material RICOH COMPANY, LTD. (JP) 1982-10-05 US claimed
EP-0036534-A1 An orally administrable drug form comprising a beta-lactam antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-30 EP claimed
EP-0036145-A1 An orally administered drug form comprising a polar bioactive agent and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-23 EP claimed
EP-0035770-A2 An orally administered drug form comprising a glycosidic antibiotic and an adjuvant INTERx RESEARCH CORPORATION (US) 1981-09-16 EP claimed
US-4279870-A Liquid-liquid extraction process for the recovery of tungsten from low level sources GTE LABORATORIES INCORPORATED (US) 1981-07-21 US claimed
EP-0031561-A2 A rectally administered suppository comprising a drug and an adjuvant MERCK & CO. INC. (US) 1981-07-08 EP claimed
US-4203619-A HEATING THE COATING CONTAINING A CHROMOGENIC MATERIAL, COOLING AND SETTING; SOLVENT-FREE THE MEAD CORPORATION (US) 1980-05-20 US claimed
US-4159208-A REACTING ALKALI METAL SALT OF AN AROMATIC CARBOXYLIC ACID AND A METAL SALT IN THE PRESENCE OF CLAY AND ALUMINUM COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1979-06-26 US claimed
US-4025609-A CHELATION KAO SOAP CO., LTD. (JA) 1977-05-24 US claimed
US-3931228-A Process for preparing phthalide and naphthalide indicator dyes POLAROID CORPORATION (US) 1976-01-06 US claimed