Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.41 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.40 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25294125 | 0.90 | DRD2 (0.43) | DRD2TBXA2RCSNK2A2CSNK2BCNR1 | |
| SCHEMBL30486976 | 0.90 | DRD2 (0.43) | DRD2TBXA2RCSNK2A2CSNK2BCNR1 | |
| SCHEMBL25282610 | 0.90 | DRD2 (0.44) | DRD2TBXA2RCSNK2A2CSNK2BF2 | |
| SCHEMBL30487001 | 0.85 | DRD2 (0.48) | DRD2TBXA2RCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL25242985 | 0.80 | CSNK2A1 (0.46) | CSNK2A2CSNK2BCSNK2A1KDM4EMAPT | |
| SCHEMBL2117975 | 0.80 | DRD2 (0.57) | DRD2TBXA2RF2NPC1RAB9A | |
| SCHEMBL30487011 | 0.80 | PDE5A (0.49) | CSNK2A2CSNK2BCSNK2A1MAPTRXFP1 | |
| SCHEMBL25252495 | 0.80 | PDE5A (0.49) | CSNK2A2CSNK2BCSNK2A1MAPTRXFP1 | |
| SCHEMBL25789845 | 0.79 | CSNK2A1 (0.45) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL30486957 | 0.79 | CSNK2A1 (0.45) | CSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023126951-A1 | INHIBITORS OF AUTOPHAGY-RELATED PROTEIN-PROTEIN INTERACTIONS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-07-06 | — | — | WO | disclosed |