Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KHK | P50053 | 16/20 | 0.59 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP4 | P49662 | 1/20 | 0.44 |
| ▸ | CASP5 | P51878 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954196 | 1.00 | KHK (0.59) | KHKPDE10AADRB1CASP1CASP4 | |
| SCHEMBL25291571 | 1.00 | KHK (0.59) | KHKPDE10AADRB1CASP1CASP4 | |
| SCHEMBL30456470 | 0.88 | KHK (0.62) | KHKPDE10A | |
| SCHEMBL30455765 | 0.84 | KHK (0.58) | KHKPDE10A | |
| SCHEMBL25245366 | 0.84 | KHK (0.65) | KHKPDE10A | |
| SCHEMBL25290857 | 0.84 | KHK (0.65) | KHKPDE10A | |
| SCHEMBL30454929 | 0.84 | KHK (0.65) | KHKPDE10A | |
| SCHEMBL25245072 | 0.82 | KHK (0.68) | KHKPDE10A | |
| SCHEMBL25289832 | 0.82 | KHK (0.68) | KHKPDE10A | |
| SCHEMBL24699193 | 0.82 | KHK (0.65) | KHKPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4434982-A1 | (S)-2-(2-METHYLAZETIDIN-1-YL)PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | LG Chem, Ltd. (KR) | 2024-09-25 | — | — | EP | disclosed |
| WO-2023121378-A1 | (S)-2-(2-METHYLAZETIDIN-1-YL)PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 엘지화학 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023121378-A1 | (S)-2-(2-METHYLAZETIDIN-1-YL)PYRIMIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 엘지화학 | 2023-06-29 | — | — | WO | disclosed |