Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814136 | 0.88 | AKR1C3 (0.71) | HTTAKR1C3MEN1KMT2APOLB | |
| SCHEMBL7814134 | 0.88 | AKR1C3 (0.71) | HTTAKR1C3MEN1KMT2APOLB | |
| SCHEMBL2951324 | 0.86 | MEN1 (0.62) | HTTAKR1C3MEN1KMT2APOLB | |
| SCHEMBL2951322 | 0.86 | MEN1 (0.62) | HTTAKR1C3MEN1KMT2APOLB | |
| SCHEMBL2523113 | 0.86 | MEN1 (0.62) | HTTAKR1C3MEN1KMT2APOLB | |
| SCHEMBL13744294 | 0.82 | AKR1C2 (0.76) | HTTAKR1C3MEN1KMT2APOLB | |
| SCHEMBL28696305 | 0.81 | HTT (0.63) | HTTMEN1KMT2APOLBSLC22A6 | |
| SCHEMBL28346803 | 0.81 | HTT (0.63) | HTTMEN1KMT2APOLBSLC22A6 | |
| SCHEMBL14125351 | 0.81 | CXCL12 (0.62) | HTTAKR1C3MEN1KMT2APOLB | |
| SCHEMBL10665004 | 0.81 | AKR1C3 (0.69) | HTTAKR1C3MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039513-B2 | Cis-1,2-substituted stilbene derivatives and their use in preparation of drugs for treatment and/or prevention of diabetes | INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) | 2011-10-18 | — | — | US | disclosed |