Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | TPMT | P51580 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7814134 | 1.00 | AKR1C3 (0.71) | AKR1C3KDM4EHTTTNFRSF1AMEN1 | |
| SCHEMBL10665004 | 0.92 | AKR1C3 (0.69) | AKR1C3KDM4EHTTTNFRSF1AMEN1 | |
| SCHEMBL10664994 | 0.92 | AKR1C3 (0.69) | AKR1C3KDM4EHTTTNFRSF1AMEN1 | |
| SCHEMBL5314275 | 0.89 | KDM4E (0.80) | AKR1C3KDM4EHTTTNFRSF1AMEN1 | |
| SCHEMBL5314277 | 0.89 | KDM4E (0.80) | AKR1C3KDM4EHTTTNFRSF1AMEN1 | |
| SCHEMBL7429368 | 0.88 | TNFRSF1A (0.58) | AKR1C3KDM4EHTTTNFRSF1AMEN1 | |
| SCHEMBL12507695 | 0.88 | AKR1C3 (0.68) | AKR1C3KDM4EHTTTNFRSF1AMEN1 | |
| SCHEMBL2524591 | 0.88 | HTT (0.58) | AKR1C3KDM4EHTTMEN1KMT2A | |
| SCHEMBL10386514 | 0.87 | AKR1C3 (0.57) | AKR1C3KDM4EHTTTNFRSF1AMEN1 | |
| SCHEMBL13744294 | 0.85 | AKR1C2 (0.76) | AKR1C3KDM4EHTTTNFRSF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |