SCHEMBL25246325

SCHEMBL25246325

CCCCCCCCNC(=O)C(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1C

nearest known ligand 0.82

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 8/20 0.82
CNR1 P21554 9/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25237402 1.00 CNR2 (0.82) CNR2CNR1
SCHEMBL25286196 1.00 CNR2 (0.82) CNR2CNR1
SCHEMBL30949048 0.99 CNR2 (0.82) CNR2CNR1
SCHEMBL25240259 0.96 CNR2 (0.82) CNR2CNR1
SCHEMBL30949050 0.92 CNR2 (0.81) CNR2CNR1
SCHEMBL22244830 0.90 CNR2 (1.00) CNR2CNR1
SCHEMBL7134748 0.90 CNR2 (1.00) CNR2CNR1
SCHEMBL31729573 0.90 CNR2 (1.00) CNR2CNR1
SCHEMBL22244859 0.90 CNR2 (1.00) CNR2CNR1
SCHEMBL7131677 0.89 CNR2 (1.00) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4652994-A1 COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY SKIN DISEASES, CONTAINING 1H-PYRAZOLE-3-AMIDE COMPOUND DERIVATIVE Ajou University Industry-Academic Cooperation Foundation (KR) 2025-11-26 EP claimed
US-20240382455-A1 COMPOSITION CONTAINING 1H-PYRAZOLE-3-AMIDE-BASED COMPOUND DERIVATIVE FOR PREVENTION OR TREATMENT OF FIBROSIS TSD LIFE SCIENCES CO., LTD. (KR) 2024-11-21 US claimed
WO-2024154884-A1 COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY SKIN DISEASES, CONTAINING 1H-PYRAZOLE-3-AMIDE COMPOUND DERIVATIVE 아주대학교산학협력단 2024-07-25 WO claimed
US-20230172908-A1 COMPOSITION CONTAINING 1H-PYRAZOLE-3-AMIDE-BASED COMPOUND DERIVATIVE FOR PREVENTION OR TREATMENT OF FIBROSIS TSD LIFE SCIENCES CO., LTD. (KR) 2023-06-08 US claimed
EP-4652994-A1 COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY SKIN DISEASES, CONTAINING 1H-PYRAZOLE-3-AMIDE COMPOUND DERIVATIVE Ajou University Industry-Academic Cooperation Foundation (KR) 2025-11-26 EP disclosed
US-20240382455-A1 COMPOSITION CONTAINING 1H-PYRAZOLE-3-AMIDE-BASED COMPOUND DERIVATIVE FOR PREVENTION OR TREATMENT OF FIBROSIS TSD LIFE SCIENCES CO., LTD. (KR) 2024-11-21 US disclosed
WO-2024154884-A1 COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY SKIN DISEASES, CONTAINING 1H-PYRAZOLE-3-AMIDE COMPOUND DERIVATIVE 아주대학교산학협력단 2024-07-25 WO disclosed
US-20230172908-A1 COMPOSITION CONTAINING 1H-PYRAZOLE-3-AMIDE-BASED COMPOUND DERIVATIVE FOR PREVENTION OR TREATMENT OF FIBROSIS TSD LIFE SCIENCES CO., LTD. (KR) 2023-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240382455-A1 COMPOSITION CONTAINING 1H-PYRAZOLE-3-AMIDE-BASED COMPOUND DERIVATIVE FOR PREVENTION OR TREATMENT OF FIBROSIS HDAC3, IL33, HDAC1 CNR2 2063/4885CNR1 1762/4885
US-20230172908-A1 COMPOSITION CONTAINING 1H-PYRAZOLE-3-AMIDE-BASED COMPOUND DERIVATIVE FOR PREVENTION OR TREATMENT OF FIBROSIS HDAC3, IL33, HDAC1 CNR2 2063/4885CNR1 1762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.