SCHEMBL25248481

SCHEMBL25248481

CCOC(=O)c1ccc(C(=O)OCCO)c(OCCO)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B2 P37059 1/20 0.50
CA12 O43570 3/20 0.48
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
CA7 P43166 3/20 0.48
CA9 Q16790 3/20 0.48
CA14 Q9ULX7 3/20 0.48
CYP1A2 P05177 3/20 0.45
CYP2D6 P10635 2/20 0.45
SCN1A P35498 2/20 0.45
SCN2A Q99250 2/20 0.45
SCN3A Q9NY46 2/20 0.45
TSHR P16473 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
KCNH2 Q12809 1/20 0.45
HIF1A Q16665 1/20 0.45
HRH3 Q9Y5N1 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25287265 1.00 HSD17B2 (0.50) HSD17B2CA12CA1CA2CA7
SCHEMBL29187221 0.90 KDM4E (0.56) CYP1A2CYP2D6SCN1ASCN2ASCN3A
SCHEMBL28904619 0.84 HSD17B2 (0.51) HSD17B2CA12CA1CA2CA7
SCHEMBL5712780 0.84 CYP1A2 (0.41) CYP1A2CYP2D6SCN1ASCN2ASCN3A
SCHEMBL31325086 0.84 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL27493026 0.83 TSHR (0.51) HSD17B2CYP1A2CYP2D6SCN1ASCN2A
SCHEMBL28750216 0.82 HSD17B2 (0.49) HSD17B2CA12CA1CA2CA7
SCHEMBL15574252 0.82 HSD17B2 (0.62) HSD17B2TSHRKDM4EPOLBLMNA
SCHEMBL8463263 0.81 HSD17B2 (0.48) HSD17B2CA12CA1CA2CA7
SCHEMBL13529210 0.80 CA12 (0.62) HSD17B2CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023110538-A1 BIS(2-HYDROXYETHYL) TEREPHTHALATE WITH LOW NITROGEN CONTENT IFP Energies Nouvelles (FR) 2023-06-22 WO claimed
CN-118271165-A Composition and method for preparing same 财团法人工业技术研究院 2024-07-02 CN disclosed
WO-2024083724-A1 BIS(2-HYDROXYETHYL)TEREPHTHALATE SOLID HAVING A PARTICULAR CRYSTAL FORM IFP Energies Nouvelles (FR) 2024-04-25 WO disclosed
CN-117916220-A Process for purifying terephthalic acid diester monomers by adsorption IFP 新能源公司 2024-04-19 CN disclosed
CN-117651734-A Process for preparing purified and decolorized diester monomers by depolymerization of polyester starting materials IFP 新能源公司 2024-03-05 CN disclosed
CN-107417526-A Process for preparing cyclohexanediol esters and derivatives thereof 远东新世纪股份有限公司 2017-12-01 CN disclosed