Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8774940 | 0.86 | KDM4E (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15528629 | 0.82 | KDM4E (0.65) | KDM4EL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL28904619 | 0.82 | HSD17B2 (0.51) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL9379667 | 0.82 | ALDH1A1 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL25248481 | 0.81 | HSD17B2 (0.50) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL27493026 | 0.81 | TSHR (0.51) | HSD17B2ALDH1A1LMNATP53ESR1 | |
| SCHEMBL25287265 | 0.81 | HSD17B2 (0.50) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL8461962 | 0.81 | KDM4E (0.43) | KDM4EL3MBTL1TDP1ALDH1A1CYP1A2 | |
| SCHEMBL28750216 | 0.80 | HSD17B2 (0.49) | HSD17B2CA12CA1CA2CA7 | |
| SCHEMBL12787213 | 0.79 | L3MBTL1 (0.46) | HSD17B2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641832-B1 | Diorganopolysiloxane-Rigid aromatic polymer compositions and preparation thereof | DOW CORNING ASIA LTD (JP) | 1999-01-13 | — | — | EP | disclosed |
| EP-0641831-B1 | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA LTD (JP) | 1997-11-12 | — | — | EP | disclosed |
| US-5527862-A | COMPATIBLE BLENDS; REINFORCED CURED COMPOSITES; HIGH STRENGTH | DOW CORNING ASIA, LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| US-5464922-A | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA LTD. (JP) | 1995-11-07 | — | — | US | disclosed |
| EP-0641832-A1 | Diorganopolysiloxane-Rigid aromatic polymer compositions and preparation thereof | DOW CORNING ASIA, Ltd. (JP) | 1995-03-08 | — | — | EP | disclosed |
| EP-0641831-A1 | Organopolysiloxane-grafted polybenzobisoxazoles and method for preparing same | DOW CORNING ASIA, Ltd. (JP) | 1995-03-08 | — | — | EP | disclosed |