Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 3/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29268951 | 1.00 | HDAC1 (0.47) | HDAC1HDAC6GRIN2BGRIN1CYP2C9 | |
| SCHEMBL29268945 | 1.00 | HDAC1 (0.47) | HDAC1HDAC6GRIN2BGRIN1CYP2C9 | |
| SCHEMBL25304282 | 0.90 | HDAC1 (0.47) | HDAC1HDAC6GRIN2BGRIN1CYP2C9 | |
| SCHEMBL30473989 | 0.90 | HDAC1 (0.44) | HDAC1HDAC6GRIN2BGRIN1CYP2C9 | |
| SCHEMBL29269042 | 0.89 | HDAC1 (0.38) | HDAC1HDAC6FAAH | |
| SCHEMBL25262089 | 0.89 | HDAC1 (0.38) | HDAC1HDAC6FAAH | |
| SCHEMBL29269038 | 0.89 | HDAC1 (0.38) | HDAC1HDAC6FAAH | |
| SCHEMBL25247673 | 0.88 | HDAC1 (0.46) | HDAC1HDAC6GRIN2BGRIN1CYP2C9 | |
| SCHEMBL25213510 | 0.86 | FAAH (0.46) | HDAC1HDAC6FAAHCES1 | |
| SCHEMBL25258959 | 0.86 | HDAC1 (0.50) | HDAC1HDAC6GRIN2BGRIN1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099561-A1 | SUBSTITUTED N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2023-06-08 | — | — | WO | disclosed |