⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10404340 | 0.71 | CCR2 (0.32) | — | |
| SCHEMBL8380024 | 0.69 | CCR2 (0.32) | — | |
| SCHEMBL19099788 | 0.69 | — | — | |
| SCHEMBL7634473 | 0.68 | — | — | |
| SCHEMBL27288275 | 0.67 | POLB (0.31) | — | |
| SCHEMBL23501558 | 0.67 | TP53 (0.32) | — | |
| SCHEMBL10940131 | 0.63 | — | — | |
| SCHEMBL7749991 | 0.63 | — | — | |
| SCHEMBL2119425 | 0.60 | FFAR3 (0.40) | — | |
| SCHEMBL22362544 | 0.58 | TSHR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8232360-B2 | Stereoregular ROMP polymers | RESEARCH FOUNDATION OF STATE UNIVERSITY OF N.Y. (US) | 2012-07-31 | — | — | US | disclosed |
| US-8232360-B2 | Stereoregular ROMP polymers | RESEARCH FOUNDATION OF STATE UNIVERSITY OF N.Y. (US) | 2012-07-31 | — | — | US | disclosed |
| US-8232360-B2 | Stereoregular ROMP polymers | RESEARCH FOUNDATION OF STATE UNIVERSITY OF N.Y. (US) | 2012-07-31 | — | — | US | disclosed |
| US-20110251363-A1 | STEREOREGULAR ROMP POLYMERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-10-13 | — | — | US | disclosed |
| US-20110251363-A1 | STEREOREGULAR ROMP POLYMERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-10-13 | — | — | US | disclosed |
| US-20110251363-A1 | STEREOREGULAR ROMP POLYMERS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-10-13 | — | — | US | disclosed |
| WO-2008019217-A2 | STEREOREGULAR ROMP POLYMERS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-02-14 | — | — | WO | disclosed |
| WO-2008019217-A2 | STEREOREGULAR ROMP POLYMERS | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-02-14 | — | — | WO | disclosed |