Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27793337 | 0.88 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTLMNANPC1RAB9A | |
| SCHEMBL31264704 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2MAPTLMNANPC1RAB9A | |
| SCHEMBL25286316 | 0.86 | NPC1 (0.50) | SMN1; SMN2MAPTLMNANPC1RAB9A | |
| SCHEMBL31264745 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2MAPTLMNANPC1RAB9A | |
| SCHEMBL28788178 | 0.79 | RECQL (0.63) | SMN1; SMN2MAPTLMNANPC1RAB9A | |
| SCHEMBL27814987 | 0.79 | ALDH1A1 (0.65) | SMN1; SMN2MAPTLMNANPC1RAB9A | |
| SCHEMBL31264719 | 0.78 | SMN1; SMN2 (0.63) | SMN1; SMN2MAPTLMNANPC1RAB9A | |
| SCHEMBL22372601 | 0.77 | USP30 (0.62) | SMN1; SMN2MAPTLMNANPC1RAB9A | |
| SCHEMBL31264796 | 0.76 | SMN1; SMN2 (0.65) | SMN1; SMN2MAPTLMNANPC1RAB9A | |
| SCHEMBL830131 | 0.75 | SMN1; SMN2 (0.72) | SMN1; SMN2MAPTLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4204415-A1 | HETEROCYCLIC GLP-1 AGONISTS | Gasherbrum Bio, Inc. (US) | 2023-07-05 | — | — | EP | disclosed |