Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 15/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25242771 | 0.89 | TYK2 (0.50) | TYK2POLBGAAAKR1C3 | |
| SCHEMBL25243819 | 0.88 | TYK2 (0.66) | TYK2POLBGAAAKR1C3 | |
| SCHEMBL25241314 | 0.86 | TYK2 (0.48) | TYK2POLBGAAAKR1C3 | |
| SCHEMBL30475043 | 0.86 | TYK2 (0.47) | TYK2POLBGAAALDH1A1AKR1C3 | |
| SCHEMBL25285748 | 0.86 | TYK2 (0.47) | TYK2POLBGAAALDH1A1AKR1C3 | |
| SCHEMBL25243602 | 0.86 | TYK2 (0.49) | TYK2 | |
| SCHEMBL24498448 | 0.85 | TYK2 (0.51) | TYK2 | |
| SCHEMBL25246852 | 0.85 | TYK2 (0.47) | TYK2POLBGAAALDH1A1AKR1C3 | |
| SCHEMBL25292402 | 0.84 | TYK2 (0.50) | TYK2POLBGAAAKR1C3 | |
| SCHEMBL25249517 | 0.83 | TYK2 (0.50) | TYK2POLBGAAAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |