Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.51 |
| ▸ | JAK1 | P23458 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25243960 | 0.91 | TYK2 (0.54) | TYK2JAK1KCNH2 | |
| SCHEMBL25294035 | 0.85 | TYK2 (0.56) | TYK2JAK1KCNH2 | |
| SCHEMBL25289314 | 0.84 | TYK2 (0.69) | TYK2JAK1KCNH2 | |
| SCHEMBL25286198 | 0.81 | TYK2 (0.45) | TYK2JAK1 | |
| SCHEMBL25243633 | 0.80 | TYK2 (0.47) | TYK2JAK1 | |
| SCHEMBL25243233 | 0.78 | TYK2 (0.54) | TYK2JAK1KCNH2 | |
| SCHEMBL25282307 | 0.77 | TYK2 (0.54) | TYK2JAK1 | |
| SCHEMBL25244650 | 0.77 | TYK2 (0.59) | TYK2JAK1 | |
| SCHEMBL25242045 | 0.77 | TYK2 (0.58) | TYK2JAK1KCNH2 | |
| SCHEMBL25244793 | 0.74 | TYK2 (0.57) | TYK2JAK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | claimed |
| EP-4206196-A1 | PYRIMIDINE SUBSTITUTED DERIVATIVES AS TYK2 INHIBITORS | Almirall S.A. (ES) | 2023-07-05 | — | — | EP | disclosed |