Acetoacetic Acid

Acetoacetic Acid

SCHEMBL2525168

C1CCCCC1.CC(=O)CC(=O)O.CC(=O)CC(=O)O.CO.CO

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
KDM5C P41229 2/20 0.46
EGLN1 Q9GZT9 2/20 0.46
PHF8 Q9UPP1 2/20 0.46
KDM2A Q9Y2K7 2/20 0.46
KDM6B O15054 1/20 0.46
LDHA P00338 1/20 0.44
SRR Q9GZT4 1/20 0.44
FFAR3 O14843 3/20 0.42
LMNA P02545 1/20 0.41
SLC15A2 Q16348 1/20 0.41
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
HTT P42858 1/20 0.36
ALDH1A1 P00352 3/20 0.35
GLRA1 P23415 1/20 0.35
SLC6A9 P48067 1/20 0.35
OR51E2 Q9H255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetoacetic Acid SCHEMBL18261844 0.97 KDM4E (0.48) KDM4EKDM5CEGLN1PHF8KDM2A
Acetoacetic Acid SCHEMBL20594350 0.97 KDM4E (0.48) KDM4EKDM5CEGLN1PHF8KDM2A
Acetoacetic Acid SCHEMBL11704647 0.94 KDM4E (0.46) KDM4EKDM5CEGLN1PHF8KDM2A
Acetoacetic Acid SCHEMBL2553497 0.91
Acetoacetic Acid SCHEMBL21955399 0.91 LDHA (0.53) KDM4EKDM5CEGLN1PHF8KDM2A
Acetoacetic Acid SCHEMBL5698496 0.91
Acetoacetic Acid SCHEMBL1144213 0.87 LDHA (0.57) KDM4EKDM5CEGLN1PHF8KDM2A
Acetoacetic Acid SCHEMBL10941648 0.87 LDHA (0.57) KDM4EKDM5CEGLN1PHF8KDM2A
Acetoacetic Acid SCHEMBL31420005 0.87
Acetoacetic Acid SCHEMBL21402364 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3662044-B1 DETERGENT ADDITIVE DOW GLOBAL TECHNOLOGIES LLC (US) 2022-08-03 EP claimed
US-11370995-B2 Detergent additive DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-28 US claimed
US-20220056171-A1 Isocyanate Free Binder ARXADA AG (CH) 2022-02-24 US claimed
EP-3909702-A1 ISOCYANATE FREE BINDER Lonza Solutions AG (CH) 2021-11-17 EP claimed
US-11162056-B2 Encapsulation method DOW GLOBAL TECHNOLOGIES LLC (US) 2021-11-02 US claimed
CN-113438992-A Isocyanate-free adhesives 隆萨解决方案股份公司 2021-09-24 CN claimed
EP-3860780-A1 ISOCYANATE FREE BINDER Lonza Solutions AG (CH) 2021-08-11 EP claimed
EP-3662049-B1 ENCAPSULATION METHOD DOW GLOBAL TECHNOLOGIES LLC (US) 2021-05-05 EP claimed
WO-2020127611-A1 ISOCYANATE FREE BINDER LONZA LTD (CH) 2020-06-25 WO claimed
US-20200181534-A1 DETERGENT ADDITIVE DOW GLOBAL TECHNOLOGIES LLC 2020-06-11 US claimed
EP-1453892-A1 SELF-PHOTOINITIATING MULTIFUNCTIONAL ACRYLATES Ashland Inc. (US) 2004-09-08 EP claimed
US-20040115437-A1 Dual cure reaction products of self-photoinitiating multifunction acrylates with cycloaliphatic epoxy compounds ASHLAND INC. (US) 2004-06-17 US claimed
WO-2004029118-A2 LIQUID UNCROSSLINKED MICHAEL ADDITION OLIGOMERS PREPARED IN THE PRESENCE OF A CATALYST HAVING BOTH AN EPOXY MOIETY AND A QUATERNARY SALT ASHLAND INC. (US) 2004-04-08 WO claimed
US-6706414-B1 Liquid uncrosslinked Michael addition oligomers prepared in the presence of a catalyst having both an epoxy moiety and a quaternary salt ASHLAND INC. 2004-03-16 US claimed
US-6673851-B2 COATING, ADHESIVE, LAMINATION; EXPOSURE TO ACTINIC LIGHT ASHLAND INC. 2004-01-06 US claimed
US-20030073757-A1 Self-photoinitiating multifunctional acrylates ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC 2003-04-17 US claimed
WO-2003031502-A1 SELF-PHOTOINITIATING MULTIFUNCTIONAL ACRYLATES ASHLAND INC. (US) 2003-04-17 WO claimed
WO-2001000684-A1 LIQUID OLIGOMERS CONTAINING UNSATURATION ASHLAND INC. (US) 2001-01-04 WO claimed
US-6025410-A WHICH CAN BE CROSSLINKED USING ULTRAVIOLET LIGHT WITHOUT ADDING COSTLY PHOTOINITATORS, PROTECTIVE OR DECORATIVE COATINGS, MICHAEL ADDITION REACTION OF ACETOACETATE FUNCTIONAL DONOR COMPOUNDS WITH MULTIFUNCTIONAL ACRYLATE RECEPTOR ASHLAND INC. (US) 2000-02-15 US claimed
US-5945489-A Liquid oligomers containing unsaturation ASHLAND, INC. (US) 1999-08-31 US claimed