Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.48 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.48 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.48 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19601141 | 0.85 | TLR8 (0.49) | AAK1MELKCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30626328 | 0.85 | TLR8 (0.49) | AAK1MELKCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL21180021 | 0.84 | RPS6KA3 (0.46) | RPS6KA3ABL1AAK1MELKCYP1A2 | |
| SCHEMBL21180011 | 0.83 | AAK1 (0.46) | RPS6KA3ABL1AAK1FYNMELK | |
| SCHEMBL27718711 | 0.82 | GCGR (0.44) | RPS6KA3GSK3BLIMK1AAK1MELK | |
| SCHEMBL18985984 | 0.81 | CYP11B1 (0.49) | NTRK1ABL1AAK1MELKCYP1A2 | |
| SCHEMBL30522600 | 0.81 | IMPDH2 (0.56) | NTRK1AAK1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL25300597 | 0.81 | IMPDH2 (0.56) | NTRK1AAK1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL12934590 | 0.80 | CYP1A2 (0.49) | AAK1MELKCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2382250 | 0.80 | NTRK1 (0.57) | NTRK1RPS6KA3CHEK1DAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230227427-A1 | IL-17A MODULATORS | SANOFI (FR) | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230227427-A1 | IL-17A MODULATORS | IL17A, IL2, IL15 | NTRK1 4666/4885RPS6KA3 1439/4885CHEK1 4842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.