Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 4/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | CA7 | P43166 | 4/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.55 |
| ▸ | XDH | P47989 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 6/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13286773 | 0.93 | SERPINE1 (0.70) | SERPINE1CA12CA1CA2CA7 | |
| SCHEMBL688142 | 0.87 | ESR1 (0.62) | SERPINE1CA1CA2ESR1ESR2 | |
| SCHEMBL689023 | 0.85 | ESR1 (0.62) | SERPINE1ESR1ESR2KMT2AGAA | |
| SCHEMBL3005634 | 0.84 | ESR1 (0.57) | SERPINE1CA12CA1CA2CA7 | |
| SCHEMBL31037701 | 0.84 | SERPINE1 (0.86) | SERPINE1XDHESR1ESR2KMT2A | |
| SCHEMBL1455751 | 0.84 | SERPINE1 (0.86) | SERPINE1XDHESR1ESR2KMT2A | |
| SCHEMBL9750105 | 0.82 | ALOX5 (0.59) | SERPINE1CA12CA1CA2CA7 | |
| SCHEMBL10377804 | 0.81 | ESR1 (0.57) | SERPINE1CA12CA1CA2CA7 | |
| SCHEMBL1918507 | 0.81 | KMT2A (0.71) | SERPINE1ESR1ESR2KMT2AGAA | |
| SCHEMBL2277663 | 0.81 | CA12 (0.66) | SERPINE1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110252507-A1 | TRANSGENIC PLANTS USED AS A BIOREACTOR SYSTEM | THE UNIVERSITY OF QUEENSLAND (AU) | 2011-10-13 | — | — | US | disclosed |
| US-7754943-B2 | Transgenic plants used as a bioreactor system | BSES LIMITED (AU) | 2010-07-13 | — | — | US | disclosed |
| US-20060259998-A1 | Transgenic plants used as a bioreactor system | BUREAU OF SUGAR EXPERIMENT STATIONS (AU) | 2006-11-16 | — | — | US | disclosed |
| US-4923403-A | CULTIVATING RHODOCOCCUS MUTANT ON STEROID-CONTAINING MEDIUM TO PRODUCE PHARMACEUTICAL PRECURSOR | SOUTH AFRICAN INVENTIONS DEVELOPMENT CORP. (ZA) | 1990-05-08 | — | — | US | disclosed |
| EP-0172034-A2 | Microbiological degradation of steroids | SOUTH AFRICAN INVENTIONS DEVELOPMENT CORPORATION (ZA) | 1986-02-19 | — | — | EP | disclosed |