Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 3/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.77 |
| ▸ | HTT | P42858 | 3/20 | 0.77 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.77 |
| ▸ | HPGD | P15428 | 2/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.77 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25269062 | 0.98 | KMT2A (0.75) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL25270294 | 0.94 | MEN1 (0.68) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL134242 | 0.85 | KMT2A (0.73) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL9706943 | 0.85 | KMT2A (0.73) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL29462402 | 0.85 | KMT2A (0.73) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL25273344 | 0.81 | KMT2A (0.63) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL2348940 | 0.81 | MEN1 (0.63) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL3636811 | 0.78 | MEN1 (0.51) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL31642809 | 0.77 | MAPT (0.74) | KMT2AMEN1LMNASMN1; SMN2HTT | |
| SCHEMBL34473944 | 0.77 | KMT2A (0.68) | KMT2AMEN1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107870-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KINNATE BIOPHARMA INC. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107870-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KINNATE BIOPHARMA INC. (US) | 2023-06-15 | — | — | WO | disclosed |