Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2348940 | 0.87 | MEN1 (0.63) | MAPTALOX12HTTALDH1A1NPSR1 | |
| SCHEMBL12764173 | 0.85 | MEN1 (0.69) | MAPTALOX12HTTALDH1A1NPSR1 | |
| SCHEMBL15886244 | 0.81 | NAMPT (0.56) | MAPTALOX12HTTALDH1A1NPSR1 | |
| SCHEMBL17236532 | 0.81 | KMT2A (0.68) | MAPTALOX12HTTALDH1A1NPSR1 | |
| SCHEMBL29130900 | 0.80 | POLB (0.64) | MAPTALOX12HTTALDH1A1NPSR1 | |
| SCHEMBL18664789 | 0.80 | ALDH1A1 (0.60) | ALOX12HTTALDH1A1NPSR1KMT2A | |
| SCHEMBL7823181 | 0.80 | GAA (0.78) | MAPTALOX12HTTALDH1A1NPSR1 | |
| SCHEMBL14826608 | 0.79 | MAPT (0.53) | MAPTALOX12HTTALDH1A1NPSR1 | |
| SCHEMBL8796471 | 0.79 | ALDH1A1 (0.63) | MAPTALOX12HTTALDH1A1NPSR1 | |
| SCHEMBL12764175 | 0.79 | RAB9A (0.74) | ALDH1A1NPSR1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025137606-A1 | (HETERO)ARYL NRF2 PROTEIN DEGRADERS | GANYMEDE ONCOLOGY, INC. (US) | 2025-06-26 | — | — | WO | disclosed |