Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.76 |
| ▸ | HTR2C | P28335 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25273950 | 0.88 | KDM4E (0.56) | HTR2AHTR2CKDM4ECYP1A2CYP3A4 | |
| Glemanserin SCHEMBL120012 | 0.87 | HTR2A (1.00) | HTR2AHTR2CKDM4ECYP1A2CYP3A4 | |
| SCHEMBL25218330 | 0.86 | KDM4E (0.58) | HTR2AHTR2CKDM4ECYP1A2CYP3A4 | |
| Glemanserin SCHEMBL7838106 | 0.86 | HTR2A (0.97) | HTR2AHTR2CKDM4ECYP1A2CYP3A4 | |
| SCHEMBL4164304 | 0.82 | KDM4E (0.55) | HTR2AHTR2CKDM4ECYP1A2CYP3A4 | |
| Bromide SCHEMBL4173363 | 0.81 | KDM4E (0.53) | HTR2AHTR2CKDM4ECYP1A2CYP3A4 | |
| SCHEMBL9328976 | 0.80 | HTR2A (0.84) | HTR2AHTR2CKDM4ECYP1A2CYP3A4 | |
| SCHEMBL6057184 | 0.79 | HTR2A (0.84) | HTR2AHTR2CKDM4ECYP1A2CYP3A4 | |
| SCHEMBL13391060 | 0.79 | KDM4E (0.45) | HTR2AHTR2CKDM4ECYP1A2CYP3A4 | |
| SCHEMBL25256739 | 0.79 | KDM4E (0.55) | KDM4ECYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107547-A2 | AZETIDINE AND SPIROAZETIDINE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107547-A2 | AZETIDINE AND SPIROAZETIDINE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |