Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | CCR3 | P51677 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25253155 | 0.86 | HTR2A (0.76) | KDM4ECYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL4164304 | 0.83 | KDM4E (0.55) | KDM4ECYP1A2CYP3A4CYP2D6TSHR | |
| Bromide SCHEMBL4173363 | 0.82 | KDM4E (0.53) | KDM4ECYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL4611120 | 0.78 | KDM4E (0.49) | KDM4ECYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL10350582 | 0.77 | SIGMAR1 (0.54) | CYP1A2CYP3A4CYP2D6TSHRCCR3 | |
| SCHEMBL10350000 | 0.76 | SIGMAR1 (0.53) | CYP1A2CYP3A4CYP2D6TSHRCCR3 | |
| SCHEMBL11631293 | 0.76 | IDO1 (0.45) | CYP1A2CYP3A4CYP2D6 | |
| Glemanserin SCHEMBL120012 | 0.74 | HTR2A (1.00) | KDM4ECYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL4611997 | 0.74 | L3MBTL1 (0.53) | — | |
| SCHEMBL4168265 | 0.74 | SLC6A3 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107547-A2 | AZETIDINE AND SPIROAZETIDINE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2023107547-A2 | AZETIDINE AND SPIROAZETIDINE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |