Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25296546 | 1.00 | ALOX5 (0.42) | ALOX5DAGLASLC6A9NR1H2NR1H3 | |
| SCHEMBL25255966 | 0.83 | TP53 (0.40) | ALOX5NR1H2NR1H3 | |
| SCHEMBL25295175 | 0.83 | TP53 (0.40) | ALOX5NR1H2NR1H3 | |
| SCHEMBL24326338 | 0.82 | NR1H2 (0.39) | DAGLASLC6A9NR1H2NR1H3TRPM8 | |
| SCHEMBL13881156 | 0.81 | ALOX5 (0.40) | ALOX5NR1H2NR1H3TRPM8CHRM2 | |
| SCHEMBL11241042 | 0.78 | ALOX5 (0.45) | ALOX5DAGLATRPM8MTORMEN1 | |
| SCHEMBL7374443 | 0.78 | ALOX5 (0.45) | ALOX5DAGLATRPM8MTORCASR | |
| SCHEMBL21878158 | 0.76 | ALOX5 (0.44) | ALOX5DAGLATRPM8MTORMEN1 | |
| SCHEMBL21878160 | 0.76 | ALOX5 (0.44) | ALOX5DAGLATRPM8MTORMEN1 | |
| SCHEMBL20741091 | 0.76 | DAGLA (0.41) | ALOX5DAGLASLC6A9TRPM8MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125845-A1 | HETEROAROMATIC BICYCLIC COMPOUND AND ANTIVIRAL APPLICATION THEREOF | 苏州爱科百发生物医药技术有限公司 | 2023-07-06 | — | — | WO | disclosed |
| WO-2023125845-A1 | HETEROAROMATIC BICYCLIC COMPOUND AND ANTIVIRAL APPLICATION THEREOF | 苏州爱科百发生物医药技术有限公司 | 2023-07-06 | — | — | WO | disclosed |