SCHEMBL2183692

SCHEMBL2183692

C[C@@H]1C(O)CCN1C(=O)O

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
RIPK1 Q13546 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25254512 1.00 MAPT (0.31) MAPTRIPK1
SCHEMBL21813498 1.00 MAPT (0.31) MAPTRIPK1
SCHEMBL3321320 1.00 MAPT (0.31) MAPTRIPK1
SCHEMBL3275294 1.00 MAPT (0.31) MAPTRIPK1
SCHEMBL15719049 1.00 MAPT (0.31) MAPTRIPK1
SCHEMBL4775884 0.87 DPP4 (0.36)
SCHEMBL8926181 0.87 DPP4 (0.36)
SCHEMBL24016478 0.82 ATM (0.35) MAPT
SCHEMBL24016463 0.82 ATM (0.35) MAPT
SCHEMBL24016479 0.82 ATM (0.35) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001044499-A9 MODIFIED LABELED COMPLEMENT COMPONENTS FOR IMMUNOASSAYS DIAGEN CORP (US) 2002-06-06 WO claimed
WO-2001044499-B1 MODIFIED LABELED COMPLEMENT COMPONENTS FOR IMMUNOASSAYS DIAGEN CORP (US) 2002-05-10 WO claimed
WO-2001044499-A1 MODIFIED LABELED COMPLEMENT COMPONENTS FOR IMMUNOASSAYS DIAGEN CORPORATION (US) 2001-06-21 WO claimed
CN-121971615-A Application of P4HA1 inhibitor in preparation of medicines for treating congenital megacolon-associated enterocolitis 华中科技大学同济医学院附属同济医院 2026-05-05 CN disclosed
US-9605001-B2 Production of polyketides and other natural products BUCK INSTITUTE FOR RESEARCH ON AGING (US) 2017-03-28 US disclosed
US-20150266896-A1 PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS BIOTICA TECH LTD (GB) 2015-09-24 US disclosed
EP-1521828-B1 PRODUCTION OF POLYKETIDES BUCK INST FOR RES ON AGING (US) 2015-07-01 EP disclosed
US-9040259-B2 Production of polyketides and other natural products BUCK INSTITUTE FOR RESEARCH ON AGING (US) 2015-05-26 US disclosed
US-20110165633-A1 Production of Polyketides and Other Natural Products BUCK INSTITUTE FOR RESEARCH ON AGING 2011-07-07 US disclosed
US-20100119517-A1 Use of Anti-MAdCAM Antibodies for the Treatment of Coeliac Disease and Tropical Sprue PFIZER INC 2010-05-13 US disclosed
US-7645768-B2 Production of polyketides and other natural products WYETH (US) 2010-01-12 US disclosed
WO-1998001136-A1 FORMULATIONS OF VESICANT DRUGS AND METHODS OF USE THEREOF BAYLOR COLLEGE OF MEDICINE (US) 1998-01-15 WO disclosed
US-5484816-A STABILIZED VITAMIN A COMPOSITION SHISEIDO COMPANY, LTD. (JP) 1996-01-16 US disclosed
US-4985405-A COMPLEX WITH AMINO ACID OR PROTEIN BONDON, JACQUES 1991-01-15 US disclosed
US-4824666-A Method of large scale growth of toxoplasmic microorganisms THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1989-04-25 US disclosed
EP-0281435-A1 Therapeutical product based on organic silicon compounds Gueyne, Jean (MC) 1988-09-07 EP disclosed
US-4675176-A EYE DISORDERS NORDEN LABORATORIES (US) 1987-06-23 US disclosed
EP-0033831-B1 SUBSTITUTED NAPHTHOIC ACIDS AMERICAN CYANAMID COMPANY (US) 1984-04-11 EP disclosed
WO-1982003550-A1 SUBSTITUTED NAPHTHOIC ACIDS AMERICAN CYANAMID CO (US) 1982-10-28 WO disclosed
EP-0033831-A2 Substituted naphthoic acids AMERICAN CYANAMID COMPANY (US) 1981-08-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150266896-A1 PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS FKBP14, FKBP4, FKBP2 MAPT 2947/4885RIPK1 522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.