Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.55 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | BLM | P54132 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
| ▸ | RECQL | P46063 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25257107 | 1.00 | ALOX15 (0.55) | ALOX15IGF1REGFRMAPTCYP3A4 | |
| SCHEMBL25261511 | 0.99 | ALOX15 (0.56) | ALOX15IGF1REGFRMAPTCYP3A4 | |
| SCHEMBL25300688 | 0.95 | ALOX15 (0.54) | ALOX15IGF1REGFRMAPTCYP3A4 | |
| SCHEMBL16429426 | 0.89 | ALOX15 (0.52) | ALOX15IGF1REGFRMAPTCYP3A4 | |
| SCHEMBL1893128 | 0.89 | ALOX15 (0.52) | ALOX15IGF1REGFRMAPTCYP3A4 | |
| SCHEMBL15263105 | 0.89 | ALOX15 (0.52) | ALOX15IGF1REGFRMAPTCYP3A4 | |
| SCHEMBL16429273 | 0.82 | APP (0.62) | ALOX15EGFRMAPTCYP3A4MAPK1 | |
| SCHEMBL16429275 | 0.82 | APP (0.62) | ALOX15EGFRMAPTCYP3A4MAPK1 | |
| SCHEMBL30839919 | 0.82 | APP (0.62) | ALOX15EGFRMAPTCYP3A4MAPK1 | |
| SCHEMBL27976644 | 0.82 | APP (0.62) | ALOX15EGFRMAPTCYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3423429-B1 | MODULATORS OF LIPOXYGENASE AND CYCLOOXYGENASE ENZYME ACTIVITY | UNIV DE MONCTON (CA) | 2023-07-12 | — | — | EP | claimed |