Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | FLT1 | P17948 | 1/20 | 0.51 |
| ▸ | FLT4 | P35916 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL248487 | 1.00 | RXFP1 (0.58) | RXFP1THRBALDH1A1POLBCA1 | |
| SCHEMBL22630858 | 0.90 | RXFP1 (0.61) | RXFP1THRBALDH1A1POLBCA1 | |
| SCHEMBL30416970 | 0.88 | GAA (0.54) | RXFP1THRBALDH1A1POLBCA1 | |
| SCHEMBL626675 | 0.88 | KMT2A (0.48) | RXFP1THRBALDH1A1POLBLMNA | |
| SCHEMBL9484064 | 0.87 | HSD17B10 (0.67) | RXFP1ALDH1A1POLBGAABDKRB1 | |
| SCHEMBL15495162 | 0.86 | RXFP1 (0.60) | RXFP1THRBALDH1A1POLBCA1 | |
| SCHEMBL9468471 | 0.85 | KMT2A (0.57) | RXFP1ALDH1A1POLBCA1CA2 | |
| SCHEMBL29419094 | 0.84 | RXFP1 (0.57) | RXFP1THRBALDH1A1POLBCA1 | |
| SCHEMBL341519 | 0.84 | RXFP1 (0.57) | RXFP1THRBALDH1A1POLBCA1 | |
| SCHEMBL14376040 | 0.84 | KDM4E (0.65) | POLBCA1CA2CA9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039014-B2 | 3′-alkoxyspirocyclopentyl-substituted tetramic and tetronic acids | BAYER CROPSCIENCE AG (DE) | 2011-10-18 | — | — | US | claimed |