SCHEMBL9484064

SCHEMBL9484064

CCOc1ccccc1C(=O)NS(=O)(=O)c1ccc(NC(=O)NC)cc1

nearest known ligand 0.67

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.67
RXFP1 Q9HBX9 7/20 0.63
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
MAPT P10636 3/20 0.55
POLB P06746 1/20 0.54
RAB9A P51151 2/20 0.53
BDKRB1 P46663 1/20 0.50
HCRTR1 O43613 1/20 0.49
MAPK1 P28482 2/20 0.48
NPC1 O15118 1/20 0.48
TP53 P04637 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ALDH1A1 P00352 1/20 0.47
KCNK3 O14649 1/20 0.47
KCNK9 Q9NPC2 1/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2525599 0.87 RXFP1 (0.58) HSD17B10RXFP1MEN1KMT2APOLB
SCHEMBL248487 0.87 RXFP1 (0.58) HSD17B10RXFP1MEN1KMT2APOLB
SCHEMBL9484652 0.81 BDKRB1 (0.56) RXFP1KMT2AMAPTPOLBRAB9A
SCHEMBL14376040 0.81 KDM4E (0.65) HSD17B10MEN1KMT2AMAPTPOLB
SCHEMBL9483024 0.79 MAPT (0.55) HSD17B10MEN1KMT2AMAPTPOLB
SCHEMBL9484328 0.79 BCAT2 (0.57) RXFP1MEN1KMT2AMAPTPOLB
SCHEMBL11773573 0.78 HSD17B10 (0.48) HSD17B10RXFP1KMT2AMAPTPOLB
SCHEMBL11777867 0.78 HSD17B10 (0.48) HSD17B10RXFP1KMT2AMAPTPOLB
SCHEMBL9484545 0.78 KAT6A (0.56) MEN1KMT2AMAPTPOLBRAB9A
SCHEMBL9468135 0.78 PLK1 (0.54) MEN1KMT2APOLBRAB9ABDKRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0365484-B1 SULFAMOYL PHENYL UREAS CIBA-GEIGY AG (CH) 1993-01-07 EP claimed
WO-2013127863-A1 USE OF AN AGROCHEMICAL COMPOSITION WITH HERBICIDAL ACTION IN CORN BASF SE (DE) 2013-09-06 WO disclosed