Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.61 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.51 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529577 | 0.98 | DGKA (0.64) | DGKANAAAHTR2CPRSS1PRSS2 | |
| SCHEMBL2531855 | 0.98 | DGKA (0.64) | DGKANAAAHTR2CPRSS1PRSS2 | |
| SCHEMBL2527426 | 0.94 | DGKA (0.70) | DGKANAAAHTR2CPRSS1PRSS2 | |
| SCHEMBL2529870 | 0.94 | DGKA (0.63) | DGKANAAAHTR2CPRSS1PRSS2 | |
| SCHEMBL7695250 | 0.92 | DGKA (0.74) | DGKANAAAHTR2CPRSS1PRSS2 | |
| SCHEMBL7688943 | 0.92 | DGKA (0.74) | DGKANAAAHTR2CPRSS1PRSS2 | |
| SCHEMBL2529725 | 0.92 | DGKA (0.74) | DGKANAAAHTR2CPRSS1PRSS2 | |
| SCHEMBL2532102 | 0.92 | DGKA (0.74) | DGKANAAAHTR2CPRSS1PRSS2 | |
| SCHEMBL2523641 | 0.92 | DGKA (0.74) | DGKANAAAHTR2CPRSS1PRSS2 | |
| SCHEMBL2533166 | 0.92 | DGKA (0.74) | DGKANAAAHTR2CPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |