Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 4/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.51 |
| ▸ | TUBB | P07437 | 5/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.51 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.51 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.51 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.51 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | LYN | P07948 | 1/20 | 0.51 |
| ▸ | BCR | P11274 | 1/20 | 0.51 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30590708 | 1.00 | SRC (0.51) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30590700 | 1.00 | SRC (0.51) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL25304040 | 1.00 | SRC (0.51) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL25304044 | 1.00 | SRC (0.51) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL25304505 | 0.92 | TUBB4A (0.61) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29059607 | 0.92 | TUBB4A (0.61) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL25304501 | 0.92 | TUBB4A (0.61) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL31264235 | 0.84 | TUBB4A (0.62) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11917531 | 0.81 | SRC (0.61) | SRCTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19863412 | 0.80 | SRC (0.47) | SRCTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134752-A1 | DIARYL COMPOUND AS TUBULIN/SRC DUAL TARGET INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-07-20 | — | — | WO | disclosed |
| CN-116444427-A | Diaryl compounds for tubulin-SRC double-target inhibitor | 武汉人福创新药物研发中心有限公司 | 2023-07-18 | — | — | CN | disclosed |