Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | SCD | O00767 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29269031 | 1.00 | FAAH (0.46) | FAAHUSP30SCDADORA3ADORA2A | |
| SCHEMBL29269036 | 1.00 | FAAH (0.46) | FAAHUSP30SCDADORA3ADORA2A | |
| SCHEMBL25241218 | 0.90 | FAAH (0.42) | FAAHUSP30SCDADORA3ADORA2A | |
| SCHEMBL30474010 | 0.90 | FAAH (0.39) | FAAHUSP30SCDADORA3ADORA2A | |
| SCHEMBL25213510 | 0.89 | FAAH (0.46) | FAAHUSP30SCDCES1HDAC1 | |
| SCHEMBL25215194 | 0.88 | FAAH (0.49) | FAAHUSP30SCDCES1HDAC1 | |
| SCHEMBL29269018 | 0.88 | FAAH (0.49) | FAAHUSP30SCDCES1HDAC1 | |
| SCHEMBL25218982 | 0.88 | FAAH (0.49) | FAAHUSP30SCDCES1HDAC1 | |
| SCHEMBL29269019 | 0.88 | FAAH (0.49) | FAAHUSP30SCDCES1HDAC1 | |
| SCHEMBL25248700 | 0.87 | FAAH (0.46) | FAAHUSP30SCDCES1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099561-A1 | SUBSTITUTED N-CYANOPYRROLIDINES WITH ACTIVITY AS USP30 INHIBITORS | MISSION THERAPEUTICS LIMITED (GB) | 2023-06-08 | — | — | WO | disclosed |