Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 9/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25297250 | 0.86 | DGAT1 (0.54) | DGAT1PTPN1BRAF | |
| SCHEMBL12372630 | 0.83 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL31512721 | 0.80 | DGAT1 (0.45) | DGAT1PTPN1P2RX7BRAF | |
| SCHEMBL1352886 | 0.80 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL14738023 | 0.79 | DGAT1 (0.42) | DGAT1PTPN1 | |
| SCHEMBL25420967 | 0.79 | DGAT1 (0.43) | DGAT1PTPN1 | |
| SCHEMBL30461686 | 0.79 | DGAT1 (0.43) | DGAT1PTPN1 | |
| SCHEMBL20588479 | 0.78 | DGAT1 (0.40) | DGAT1PTPN1P2RX7 | |
| SCHEMBL25107078 | 0.77 | DGAT1 (0.42) | DGAT1PTPN1 | |
| SCHEMBL30205728 | 0.77 | DGAT1 (0.42) | DGAT1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118488947-A | Condensed ring substituted six-membered heterocyclic compound, preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2024-08-13 | — | — | CN | disclosed |
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |