Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL228259 | 0.91 | MEN1 (0.67) | MEN1CYP2D6KMT2AHSD11B1 | |
| Hydrochloric Acid SCHEMBL224933 | 0.89 | MEN1 (0.70) | MEN1CYP2D6KMT2AHSD11B1 | |
| Bromide SCHEMBL7253785 | 0.89 | MEN1 (0.65) | MEN1CYP2D6KMT2AHSD11B1 | |
| Trifluoroacetic Acid SCHEMBL28292809 | 0.87 | MEN1 (0.55) | MEN1CYP2D6KMT2AHSD11B1 | |
| SCHEMBL8110383 | 0.84 | MEN1 (0.59) | MEN1CYP2D6KMT2AHSD11B1ALDH1A1 | |
| Bromide SCHEMBL9092341 | 0.83 | MEN1 (0.58) | MEN1CYP2D6KMT2AHSD11B1ALDH1A1 | |
| SCHEMBL2146518 | 0.81 | MEN1 (0.54) | MEN1CYP2D6KMT2AHSD11B1 | |
| SCHEMBL4240412 | 0.80 | MEN1 (0.61) | MEN1CYP2D6KMT2AHSD11B1 | |
| Hydrochloric Acid SCHEMBL5478248 | 0.80 | MEN1 (0.57) | MEN1CYP2D6KMT2AHSD11B1 | |
| Hydrochloric Acid SCHEMBL5478246 | 0.80 | MEN1 (0.57) | MEN1CYP2D6KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120004208-A1 | BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | GOBBI LUCA (CH) | 2012-01-05 | — | — | US | disclosed |
| US-8039490-B2 | Benzoyl-piperidine derivatives as dual modulators of the 5-HT2A and D3 receptors | HOFFMANN-LA ROCHE INC. (US) | 2011-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004208-A1 | BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | HTR2A, HTR3A, HTR2C | MEN1 3878/4885CYP2D6 415/4885KMT2A 856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.