Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | FABP7 | O15540 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL25297596 | 1.00 | HTT (0.52) | HTTPLA2G2CFABP7ALDH1A1MEN1 | |
| SCHEMBL308513 | 0.95 | HTT (0.56) | HTTPLA2G2CFABP7ALDH1A1MEN1 | |
| Phosphonic Acid SCHEMBL8160257 | 0.87 | HTT (0.48) | HTTPLA2G2CALDH1A1MEN1KMT2A | |
| SCHEMBL26960832 | 0.87 | HTT (0.48) | HTTPLA2G2CALDH1A1MEN1KMT2A | |
| SCHEMBL28931281 | 0.87 | HTT (0.48) | HTTPLA2G2CALDH1A1MEN1KMT2A | |
| Ether SCHEMBL17529920 | 0.85 | HTT (0.47) | HTTPLA2G2CFABP7ALDH1A1MEN1 | |
| SCHEMBL17220631 | 0.85 | ALDH1A1 (0.52) | HTTPLA2G2CALDH1A1HSD17B10CA1 | |
| SCHEMBL29184385 | 0.84 | HTT (0.45) | HTTPLA2G2C | |
| Ethyl Acetate SCHEMBL29184393 | 0.82 | ALDH1A1 (0.52) | HTTPLA2G2CALDH1A1MEN1KMT2A | |
| SCHEMBL18135323 | 0.81 | HTT (0.39) | HTTPLA2G2CALDH1A1TSHRCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023130249-A1 | ELECTROLYTE, SECONDARY BATTERY USING SAME, BATTERY MODULE, BATTERY PACK, AND ELECTRICAL DEVICE | 宁德时代新能源科技股份有限公司 | 2023-07-13 | — | — | WO | disclosed |
| CN-114946065-A | Non-aqueous electrolyte for lithium secondary battery and lithium secondary battery comprising same | 株式会社LG新能源 | 2022-08-26 | — | — | CN | disclosed |