Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 14/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.39 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30068859 | 1.00 | MAP3K12 (0.42) | MAP3K12PIK3CGMAP3K11PIK3CDPIK3CA | |
| SCHEMBL30068624 | 0.94 | MAP3K12 (0.42) | MAP3K12PIK3CGMAP3K11PIK3CDPIK3CA | |
| SCHEMBL25302375 | 0.94 | MAP3K12 (0.42) | MAP3K12PIK3CGMAP3K11PIK3CDPIK3CA | |
| SCHEMBL25302377 | 0.94 | MAP3K12 (0.42) | MAP3K12PIK3CGMAP3K11PIK3CDPIK3CA | |
| SCHEMBL25845700 | 0.93 | MAP3K12 (0.38) | MAP3K12PIK3CGMAP3K11 | |
| SCHEMBL25839914 | 0.89 | MAP3K12 (0.44) | MAP3K12PIK3CGMAP3K11PIK3CDPIK3CA | |
| SCHEMBL25300804 | 0.87 | PIK3CG (0.42) | MAP3K12PIK3CG | |
| SCHEMBL31150882 | 0.87 | PIK3CG (0.42) | MAP3K12PIK3CG | |
| SCHEMBL30068532 | 0.87 | PIK3CG (0.42) | MAP3K12PIK3CG | |
| SCHEMBL29150712 | 0.87 | PIK3CG (0.42) | MAP3K12PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4303216-A1 | FUSED RING SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2024-01-10 | — | — | EP | disclosed |
| CN-116981661-A | Condensed ring substituted six-membered heterocyclic compound, preparation method and application thereof | 劲方医药科技(上海)有限公司 | 2023-10-31 | — | — | CN | disclosed |
| WO-2023131122-A1 | FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2023-07-13 | — | — | WO | disclosed |