SCHEMBL25845700 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	MAP3K12	Q12852	7/20	0.38

▸	MAP3K11	Q16584	1/20	0.36

▸	OPRL1	P41146	2/20	0.35

▸	OPRM1	P35372	1/20	0.35

▸	OPRK1	P41145	1/20	0.35

▸	FAAH	O00519	1/20	0.35

▸	PIK3CG	P48736	9/20	0.34

▸	CYP1A2	P05177	1/20	0.33

▸	CYP3A4	P08684	1/20	0.33

▸	CYP2D6	P10635	1/20	0.33

▸	CYP2C9	P11712	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL25258943	0.93	MAP3K12 (0.42)	MAP3K12MAP3K11PIK3CG
SCHEMBL30068859	0.93	MAP3K12 (0.42)	MAP3K12MAP3K11PIK3CG
SCHEMBL30491229	0.87	PIK3CG (0.41)	MAP3K12MAP3K11PIK3CGCYP1A2CYP3A4
SCHEMBL25299525	0.87	PIK3CG (0.41)	MAP3K12MAP3K11PIK3CGCYP1A2CYP3A4
SCHEMBL25299524	0.87	PIK3CG (0.41)	MAP3K12MAP3K11PIK3CGCYP1A2CYP3A4
SCHEMBL25302377	0.87	MAP3K12 (0.42)	MAP3K12MAP3K11PIK3CG
SCHEMBL30068624	0.87	MAP3K12 (0.42)	MAP3K12MAP3K11PIK3CG
SCHEMBL25302375	0.87	MAP3K12 (0.42)	MAP3K12MAP3K11PIK3CG
SCHEMBL30491534	0.86	MAP4K1 (0.39)	MAP3K12MAP3K11PIK3CG
SCHEMBL30068869	0.86	MAP3K12 (0.36)	MAP3K12MAP3K11PIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023131122-A1	FUSED RING-SUBSTITUTED SIX-MEMBERED HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF	劲方医药科技(上海)有限公司	2023-07-13	—	—	WO	disclosed