Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 10/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 9/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.33 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12211607 | 0.82 | CYP3A4 (0.34) | CYP3A4CYP3A5SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL12211663 | 0.81 | BRD4 (0.39) | CYP3A4CYP3A5SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL2198693 | 0.81 | NPC1 (0.40) | CYP3A4CYP3A5SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL2525265 | 0.80 | SMN1; SMN2 (0.38) | CYP3A4CYP3A5SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL12211674 | 0.79 | CYP3A4 (0.38) | CYP3A4CYP3A5ATMGABRA5 | |
| SCHEMBL12211716 | 0.79 | ATM (0.37) | CYP3A4CYP3A5SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL18707644 | 0.79 | ATM (0.37) | CYP3A4CYP3A5SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL29369392 | 0.79 | ATM (0.39) | CYP3A4CYP3A5SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL3114118 | 0.79 | ATM (0.39) | CYP3A4CYP3A5SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL29367523 | 0.79 | ATM (0.39) | CYP3A4CYP3A5SMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | SYNGENTA CROP PROTECTION LLC (US) | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251066-A1 | ISOXAZOLE DERIVATIVES FOR USE AS PLANT GROWTH REGULATORS | CYP4Z1, CYP4X1, AGXT | CYP3A4 981/4885CYP3A5 430/4885SMN1; SMN2 4879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.