Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 5/20 | 0.32 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2530019 | 0.98 | EPHX2 (0.44) | EPHX2DNM1FAAHLPAR1LPAR3 | |
| SCHEMBL2530066 | 0.98 | EPHX2 (0.44) | EPHX2DNM1FAAHLPAR1LPAR3 | |
| SCHEMBL27203931 | 0.94 | EPHX2 (0.38) | EPHX2DNM1FAAHLPAR1LPAR3 | |
| SCHEMBL2528776 | 0.94 | EPHX2 (0.40) | EPHX2DNM1FAAHCNR1CNR2 | |
| SCHEMBL27203941 | 0.90 | EPHX2 (0.35) | EPHX2DNM1FAAHCNR1CNR2 | |
| SCHEMBL2527830 | 0.89 | EPHX2 (0.35) | EPHX2DNM1 | |
| SCHEMBL2529833 | 0.88 | EPHX2 (0.36) | EPHX2DNM1LPAR1LPAR3 | |
| SCHEMBL16599773 | 0.88 | FAAH (0.39) | EPHX2DNM1FAAHCNR1CNR2 | |
| SCHEMBL2533953 | 0.88 | EPHX2 (0.36) | EPHX2DNM1LPAR1LPAR3 | |
| SCHEMBL2529150 | 0.87 | EPHX2 (0.38) | EPHX2DNM1FAAHCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |