Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 8/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30589659 | 1.00 | FASN (0.46) | FASNPRKAA2FPR2EPHX2GRM5 | |
| SCHEMBL23675241 | 0.89 | FASN (0.43) | FASNPRKAA2FPR2EPHX2GRM5 | |
| SCHEMBL29565245 | 0.89 | FASN (0.43) | FASNPRKAA2FPR2EPHX2GRM5 | |
| SCHEMBL30589648 | 0.86 | GRM5 (0.60) | FASNGRM5NOS1NOS2CYP3A4 | |
| SCHEMBL25300159 | 0.86 | GRM5 (0.60) | FASNGRM5NOS1NOS2CYP3A4 | |
| SCHEMBL25296254 | 0.83 | GRM5 (0.58) | FASNPRKAA2GRM5ALDH1A1 | |
| SCHEMBL30589653 | 0.83 | GRM5 (0.58) | FASNPRKAA2GRM5ALDH1A1 | |
| SCHEMBL23680626 | 0.75 | GRM5 (0.46) | GRM5ALDH1A1 | |
| SCHEMBL24929603 | 0.75 | FASN (0.46) | FASNFPR2EPHX2NOS1NOS2 | |
| SCHEMBL24329653 | 0.73 | GRM5 (0.42) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023137356-A1 | 15-PGDH INHIBITORS | VENTYX BIOSCIENCES, INC. (US) | 2023-07-20 | — | — | WO | disclosed |
| WO-2023137356-A1 | 15-PGDH INHIBITORS | VENTYX BIOSCIENCES, INC. (US) | 2023-07-20 | — | — | WO | disclosed |