Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 12/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23680626 | 0.88 | GRM5 (0.46) | GRM5LRRK2TDP1VNN1HPGD | |
| SCHEMBL24929595 | 0.79 | GRM5 (0.46) | GRM5LRRK2HPGD | |
| SCHEMBL24929599 | 0.77 | GRM5 (0.50) | GRM5LRRK2VNN1HPGD | |
| SCHEMBL29565025 | 0.75 | GRM5 (0.41) | GRM5LRRK2VNN1HPGDGRM4 | |
| SCHEMBL29564740 | 0.75 | GRM5 (0.48) | GRM5LRRK2VNN1HPGD | |
| SCHEMBL23675265 | 0.75 | GRM5 (0.48) | GRM5LRRK2VNN1HPGD | |
| SCHEMBL23675258 | 0.75 | GRM5 (0.41) | GRM5LRRK2VNN1HPGDGRM4 | |
| SCHEMBL25259875 | 0.73 | FASN (0.46) | GRM5 | |
| SCHEMBL30589659 | 0.73 | FASN (0.46) | GRM5 | |
| SCHEMBL28883063 | 0.73 | HPGD (0.50) | HPGDNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082009-A1 | INHALED FORMULATIONS OF PGDH INHIBITORS AND METHODS OF USE THEREOF | EPIRIUM BIO INC. (US) | 2022-04-21 | — | — | WO | disclosed |