Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 15/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30581457 | 1.00 | STING1 (0.47) | STING1ENPP1NPC1RAB9ASMPD1 | |
| SCHEMBL25262670 | 0.88 | SMN1; SMN2 (0.44) | STING1POLBMAPT | |
| SCHEMBL30586457 | 0.88 | SMN1; SMN2 (0.44) | STING1POLBMAPT | |
| SCHEMBL25258702 | 0.87 | TSHR (0.48) | STING1MAPT | |
| SCHEMBL30586485 | 0.87 | TSHR (0.48) | STING1MAPT | |
| SCHEMBL25263480 | 0.86 | KMT2A (0.50) | STING1ENPP1 | |
| SCHEMBL31000978 | 0.86 | KMT2A (0.50) | STING1ENPP1 | |
| SCHEMBL19437552 | 0.83 | STING1 (0.52) | STING1 | |
| SCHEMBL29692138 | 0.82 | STING1 (0.57) | STING1ENPP1 | |
| SCHEMBL19437504 | 0.82 | STING1 (0.57) | STING1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116444544-A | Benzimidazole compound and medical application thereof | 中国科学院上海药物研究所 | 2023-07-18 | — | — | CN | disclosed |
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |
| WO-2023131333-A1 | BENZIMIDAZOLE COMPOUND AND MEDICAL USE THEREOF | 中国科学院上海药物研究所 | 2023-07-13 | — | — | WO | disclosed |