SCHEMBL25260653

SCHEMBL25260653

CCOC(=O)c1cc2cc(CP(=O)(OCC)OCC)c(F)cc2n1C(=O)OC(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ NOD2 Q9HC29 3/20 0.34
▸ NOD1 Q9Y239 3/20 0.34
▸ DPP4 P27487 1/20 0.32
▸ MAPT P10636 4/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ HTT P42858 2/20 0.31
▸ POLB P06746 1/20 0.31
▸ MEN1 O00255 1/20 0.30
▸ NR1H2 P55055 2/20 0.30
▸ NPC1 O15118 1/20 0.30
▸ RAB9A P51151 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30
▸ NR1H3 Q13133 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30527551 1.00 NOD2 (0.34) NOD2NOD1DPP4MAPTALDH1A1
SCHEMBL25263110 0.90 DPP4 (0.33) DPP4ALDH1A1NR1H2NR1H3
SCHEMBL25887665 0.90 DPP4 (0.31) DPP4
SCHEMBL25299659 0.85 NOD2 (0.37) NOD2NOD1DPP4MAPTALDH1A1
SCHEMBL30527567 0.85 NOD2 (0.37) NOD2NOD1DPP4MAPTALDH1A1
SCHEMBL25308522 0.82 NOD2 (0.40) NOD2NOD1MAPTALDH1A1L3MBTL1
SCHEMBL31250412 0.82 NOD2 (0.40) NOD2NOD1MAPTALDH1A1HTT
SCHEMBL22468625 0.82 NOD2 (0.40) NOD2NOD1MAPTALDH1A1HTT
SCHEMBL5065658 0.76 NOD2 (0.47) NOD2NOD1MAPTALDH1A1L3MBTL1
SCHEMBL21685569 0.76 NOD2 (0.45) NOD2NOD1MAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250215029-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. 2025-07-03 — — US disclosed
CN-118804917-A STAT modulators and uses thereof 瑞克鲁迪克斯制药股份有限公司 2024-10-18 — — CN disclosed
WO-2023133336-A1 STAT MODULATORS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2023-07-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250215029-A1 STAT MODULATORS AND USES THEREOF STAT6, STAT3, STAT5A NOD2 1645/4885NOD1 2047/4885DPP4 1139/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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