Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.71 |
| ▸ | RECQL | P46063 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | MMP1 | P03956 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | APEX1 | P27695 | 2/20 | 0.71 |
| ▸ | BLM | P54132 | 2/20 | 0.71 |
| ▸ | HTT | P42858 | 1/20 | 0.71 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.66 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.61 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31236658 | 0.96 | POLH (0.92) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630781 | 0.96 | POLH (0.92) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630786 | 0.96 | POLH (0.92) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL31236655 | 0.96 | POLH (0.92) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL17620378 | 0.94 | POLH (0.89) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL12693930 | 0.91 | POLH (0.83) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL30663836 | 0.90 | POLH (1.00) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL25304942 | 0.90 | POLH (1.00) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL10728956 | 0.90 | POLH (1.00) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL7202826 | 0.90 | POLH (1.00) | POLHMEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215522-A1 | DERIVATIVES OF 4-CHROMONE AS INHIBITORS OF THE RDRP POLYMERASE OF SARS-COV-2 VIRUS AND METHOD FOR THE PREPARATION THEREOF | Fondazione Istituto Italiano di Tecnologia (IT) | 2023-07-26 | — | — | EP | disclosed |
| EP-4215522-A1 | DERIVATIVES OF 4-CHROMONE AS INHIBITORS OF THE RDRP POLYMERASE OF SARS-COV-2 VIRUS AND METHOD FOR THE PREPARATION THEREOF | Fondazione Istituto Italiano di Tecnologia (IT) | 2023-07-26 | — | — | EP | disclosed |
| CN-103275051-B | A kind of 7,3 ', 4 '-trihydroxyflavone derivative and preparing the application in Hepatoma therapy medicine | SHAANXI SCIENCE AND ENGINEERING COLLEGE (CN) | 2015-12-09 | — | — | CN | disclosed |