Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.69 |
| ▸ | MET | P08581 | 1/20 | 0.69 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.63 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.57 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29059811 | 0.89 | ALK (0.65) | EGFRMETALKLRRK2 | |
| SCHEMBL25306773 | 0.89 | EGFR (0.77) | EGFRMETALKLRRK2ZAP70 | |
| SCHEMBL25299463 | 0.88 | ALK (0.72) | EGFRMETALKLRRK2ZAP70 | |
| SCHEMBL29059805 | 0.87 | EGFR (0.78) | EGFRMETALKLRRK2ZAP70 | |
| SCHEMBL26495726 | 0.87 | EGFR (0.64) | EGFRMETALKLRRK2ZAP70 | |
| SCHEMBL24207052 | 0.86 | EGFR (0.80) | EGFRMETALKLRRK2ZAP70 | |
| SCHEMBL21432251 | 0.86 | EGFR (0.79) | EGFRMETALKLRRK2ZAP70 | |
| SCHEMBL25304699 | 0.86 | ALK (0.63) | EGFRMETALKLRRK2 | |
| SCHEMBL22518894 | 0.85 | EGFR (0.80) | EGFRMETALKZAP70 | |
| SCHEMBL21432306 | 0.85 | EGFR (0.73) | EGFRMETALKLRRK2ZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322723-A1 | COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF | J2H BIOTECH INC. (KR) | 2023-10-12 | — | — | US | disclosed |
| US-20230322723-A1 | COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF | J2H BIOTECH INC. (KR) | 2023-10-12 | — | — | US | disclosed |
| US-20230322723-A1 | COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF | J2H BIOTECH INC. (KR) | 2023-10-12 | — | — | US | disclosed |
| CN-116490184-A | Compounds for inhibiting EGFR mutant cancers and pharmaceutical uses thereof | J2H生物科技有限公司 | 2023-07-25 | — | — | CN | disclosed |
| EP-4212522-A1 | COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF | J2H Biotech Inc. (KR) | 2023-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322723-A1 | COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF | EGFR, KRAS, ERBB2 | EGFR 1/4885MET 14/4885ALK 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.