Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21494356 | 0.94 | PIK3CA (0.37) | PIK3CAMTORMEN1KMT2AMLYCD | |
| SCHEMBL18075678 | 0.86 | KMT2A (0.36) | PIK3CAMTORMEN1KMT2AMLYCD | |
| SCHEMBL31103821 | 0.83 | KMT2A (0.36) | PIK3CAMTORMEN1KMT2AMLYCD | |
| SCHEMBL21050898 | 0.82 | MEN1 (0.46) | PIK3CAMTORMEN1KMT2ATDP1 | |
| SCHEMBL20139638 | 0.80 | MLYCD (0.37) | PIK3CAMTORMEN1KMT2AMLYCD | |
| SCHEMBL30845490 | 0.80 | MLYCD (0.37) | PIK3CAMTORMEN1KMT2AMLYCD | |
| SCHEMBL1551558 | 0.79 | MEN1 (0.43) | PIK3CAMTORMEN1KMT2AMLYCD | |
| SCHEMBL16858435 | 0.78 | KDM4E (0.54) | POLBALDH1A1KDM4ELMNATSHR | |
| SCHEMBL6745164 | 0.77 | MEN1 (0.35) | PIK3CAMTORMEN1KMT2AMLYCD | |
| SCHEMBL21494414 | 0.76 | MLYCD (0.36) | PIK3CAMTORMEN1KMT2AMLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107870-A1 | INHIBITORS OF FIBROBLAST GROWTH FACTOR RECEPTOR KINASES | KINNATE BIOPHARMA INC. (US) | 2023-06-15 | — | — | WO | disclosed |