Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15873299 | 1.00 | CHRNB2 (0.31) | CHRNB2CHRNA4PKMCHRNB4CHRNA3 | |
| SCHEMBL2692907 | 1.00 | CHRNB2 (0.31) | CHRNB2CHRNA4PKMCHRNB4CHRNA3 | |
| SCHEMBL30301462 | 1.00 | CHRNB2 (0.31) | CHRNB2CHRNA4PKMCHRNB4CHRNA3 | |
| SCHEMBL14688917 | 0.82 | EPHX1 (0.35) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL25263000 | 0.80 | CHRNB2 (0.39) | CHRNB2CHRNA4CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL15873107 | 0.78 | BTK (0.44) | — | |
| SCHEMBL2839781 | 0.78 | BTK (0.44) | — | |
| SCHEMBL30404442 | 0.78 | BTK (0.44) | — | |
| SCHEMBL15874890 | 0.78 | BTK (0.44) | — | |
| SCHEMBL29970423 | 0.78 | BTK (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4186897-A1 | PYRIDINECARBOXAMIDE COMPOUND USEFUL AS PIM KINASE INHIBITOR | Incyte Holdings Corporation (US) | 2023-05-31 | — | — | EP | disclosed |