Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25190965 | 1.00 | CRBN (0.48) | CRBNDDB1POLBL3MBTL1GPR119 | |
| SCHEMBL25188959 | 0.87 | CRBN (0.48) | CRBNDDB1POLBL3MBTL1MAPT | |
| SCHEMBL25200407 | 0.87 | CRBN (0.48) | CRBNDDB1POLBL3MBTL1MAPT | |
| SCHEMBL25205685 | 0.86 | CRBN (0.51) | CRBNDDB1POLBGPR119 | |
| SCHEMBL25502422 | 0.85 | CRBN (0.50) | CRBNDDB1POLBL3MBTL1MAPT | |
| SCHEMBL30441494 | 0.85 | CRBN (0.50) | CRBNDDB1POLBL3MBTL1MAPT | |
| SCHEMBL29223447 | 0.84 | CRBN (0.62) | CRBNDDB1POLBGPR119 | |
| SCHEMBL25191688 | 0.83 | CRBN (0.46) | CRBNDDB1POLBL3MBTL1MAPT | |
| SCHEMBL25191709 | 0.83 | CRBN (0.46) | CRBNDDB1POLBL3MBTL1MAPT | |
| SCHEMBL25193827 | 0.83 | CRBN (0.51) | CRBNDDB1POLBGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023086399-A1 | BIFUNCTIONAL DEGRADERS OF HEMATOPOIETIC PROGENITOR KINASE AND THERAPEUTIC USES THEREOF | NURIX THERAPEUTICS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |