SCHEMBL2526554

SCHEMBL2526554

C#CCCCCP(=O)(O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.52
LPAR3 Q9UBY5 3/20 0.46
LPAR2 Q9HBW0 1/20 0.46
BBOX1 O75936 2/20 0.44
CYP3A4 P08684 2/20 0.44
LMNA P02545 1/20 0.44
NFKB1 P19838 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
MAPT P10636 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ALDH1A1 P00352 3/20 0.37
TDP1 Q9NUW8 1/20 0.37
USP2 O75604 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ENPEP Q07075 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25855289 0.98 LPAR3 (0.50) TYMSLPAR3LPAR2BBOX1CYP3A4
SCHEMBL28202074 0.98 LPAR3 (0.50) TYMSLPAR3LPAR2BBOX1CYP3A4
SCHEMBL22492270 0.98 LPAR3 (0.50) TYMSLPAR3LPAR2BBOX1CYP3A4
SCHEMBL28333340 0.98 LPAR3 (0.50) TYMSLPAR3LPAR2BBOX1CYP3A4
SCHEMBL28333338 0.98 LPAR3 (0.50) TYMSLPAR3LPAR2BBOX1CYP3A4
SCHEMBL26361982 0.92
SCHEMBL26136017 0.81
SCHEMBL20235 0.78 TYMS (0.85) TYMSLPAR3LPAR2BBOX1CYP3A4
SCHEMBL17107642 0.75 TYMS (0.52) TYMSLPAR3LPAR2BBOX1CYP3A4
SCHEMBL15537598 0.75 TYMS (0.52) TYMSLPAR3LPAR2BBOX1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110669458-B Resin composition 苏州星烁纳米科技有限公司 2021-06-29 CN disclosed
CN-110669458-A Resin composition 苏州星烁纳米科技有限公司 2020-01-10 CN disclosed
CN-107760232-B resin composition, light conversion element, and light source module 苏州星烁纳米科技有限公司 2019-12-17 CN disclosed
US-10023866-B2 Compositions and methods for inhibition of nucleic acids function Life Technologies Corporation (US) 2018-07-17 US disclosed
US-20180057814-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION Life Technologies Corporation 2018-03-01 US disclosed
US-9783804-B2 Compositions and methods for inhibition of nucleic acids function Life Technologies Corporation (US) 2017-10-10 US disclosed
US-20170009232-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION Life Technologies Corporation 2017-01-12 US disclosed
US-9410153-B2 Compositions and methods for inhibition of nucleic acids function Life Technologies Corporation (US) 2016-08-09 US disclosed
EP-2558578-B1 COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION LIFE TECHNOLOGIES CORP (US) 2015-10-28 EP disclosed
US-9145556-B2 Compositions and methods for inhibition of nucleic acids function Life Technologies Corporation (US) 2015-09-29 US disclosed
US-20150166992-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION Life Technologies Corporation (US) 2015-06-18 US disclosed
EP-2558578-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION Life Technologies Corporation (US) 2013-02-20 EP disclosed
WO-2011130371-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION Life Technologies Corporation (US) 2011-10-20 WO disclosed
US-20110251261-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION Life Technologies Corporation (US) 2011-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10023866-B2 Compositions and methods for inhibition of nucleic acids function RNGTT, NSUN3, NSUN2 TYMS 823/4885LPAR3 1002/4885LPAR2 1486/4885
US-20170009232-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION RNGTT, NSUN3, NSUN2 TYMS 823/4885LPAR3 1002/4885LPAR2 1486/4885
US-20110251261-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION RNGTT, NSUN3, NSUN2 TYMS 823/4885LPAR3 1002/4885LPAR2 1486/4885
US-20180057814-A1 COMPOSITIONS AND METHODS FOR INHIBITION OF NUCLEIC ACIDS FUNCTION RNGTT, NSUN3, NSUN2 TYMS 823/4885LPAR3 1002/4885LPAR2 1486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.