Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 14/20 | 0.78 |
| ▸ | EGFR | P00533 | 4/20 | 0.69 |
| ▸ | INSR | P06213 | 3/20 | 0.61 |
| ▸ | IGF1R | P08069 | 3/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16752958 | 0.88 | ALK (1.00) | ALKEGFRINSRLRRK2 | |
| SCHEMBL26161575 | 0.87 | ALK (0.85) | ALKEGFRINSRIGF1RKCNH2 | |
| SCHEMBL30502344 | 0.86 | ALK (0.87) | ALKEGFRINSRIGF1RKCNH2 | |
| SCHEMBL21410349 | 0.84 | EGFR (0.69) | ALKEGFRINSRIGF1RKCNH2 | |
| SCHEMBL22464424 | 0.83 | ALK (0.82) | ALKEGFRINSRIGF1RKCNH2 | |
| SCHEMBL29188606 | 0.83 | ALK (0.82) | ALKEGFRINSRIGF1RKCNH2 | |
| SCHEMBL29618204 | 0.83 | ALK (0.81) | ALKEGFRINSRIGF1RKCNH2 | |
| SCHEMBL30090709 | 0.81 | ALK (0.83) | ALKEGFRINSRIGF1RLRRK2 | |
| SCHEMBL21846999 | 0.81 | EGFR (1.00) | ALKEGFRLRRK2 | |
| SCHEMBL11916456 | 0.81 | ALK (0.85) | ALKEGFRINSRIGF1RLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |