Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 14/20 | 0.87 |
| ▸ | EGFR | P00533 | 4/20 | 0.72 |
| ▸ | INSR | P06213 | 1/20 | 0.68 |
| ▸ | IGF1R | P08069 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16752958 | 0.93 | ALK (1.00) | ALKEGFRINSRLRRK2 | |
| SCHEMBL26161575 | 0.90 | ALK (0.85) | ALKEGFRINSRIGF1RKCNH2 | |
| SCHEMBL29188606 | 0.86 | ALK (0.82) | ALKEGFRINSRIGF1RKCNH2 | |
| SCHEMBL22464424 | 0.86 | ALK (0.82) | ALKEGFRINSRIGF1RKCNH2 | |
| SCHEMBL25274302 | 0.86 | ALK (0.78) | ALKEGFRINSRIGF1RKCNH2 | |
| SCHEMBL29618204 | 0.86 | ALK (0.81) | ALKEGFRINSRIGF1RKCNH2 | |
| SCHEMBL16752902 | 0.84 | ALK (1.00) | ALK | |
| SCHEMBL21846999 | 0.84 | EGFR (1.00) | ALKEGFRLRRK2 | |
| SCHEMBL11916456 | 0.84 | ALK (0.85) | ALKEGFRINSRIGF1RLRRK2 | |
| SCHEMBL30180253 | 0.84 | ALK (0.85) | ALKEGFRINSRIGF1RLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490184-A | Compounds for inhibiting EGFR mutant cancers and pharmaceutical uses thereof | J2H生物科技有限公司 | 2023-07-25 | — | — | CN | disclosed |